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Humans Chromosome 1 Fractal Periods Signature is Highly Correlated with Intelligence and Brain Evolution

Abstract:

DUF1220 proteins regions show the largest Homo-Sapiens lineage-specific increase in copy number of any protein-coding region in the human genome and map principally to 1q21.1. DUF1220 deletions have been associated with microcephaly and macrocephaly, respectively. DUF1220 copy number has been linked to both brain size in humans and brain evolution among primates.  Remarkably, dosage variations involving DUF1220 sequences have now been linked to human brain expansion, autism severity, total IQ, and cognitive and mathematical aptitude scores. We analyzed in chromosome 1q a total of 245 DUF1220 proteins. Finally the method is extended analysing the long 1q21 region from 7 other close primates like Neanderthal, great apes : chimp, gorilla, orangutan and monkeys : macaque, marmoset, vervet. This remarkable property is confirmed by comparing these primates to other mammals such as mice, rabbit, cow, dolphin and Elephant. We then show four classes of multi-periodic f...

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Placenta Previa with History of Previous Caesarean Delivery – an Obstetrician's Nightmare

Abstract:

Background:

The nature of placenta previa can be unpredictable and harsh on the mother and baby. These complications are often unpredictable, unpreventable and often leave the labour ward team in a dilemma. This Obstetricians' nightmare is fortunately a rare complication. The frequency of placenta previa at the time of delivery average 1/200 births i.e. 0.5%. Placenta previa is still an important cause of maternal and fetal death in our country. The risk factors are Advanced Maternal age, Multi parity, Previous Cesarean Section, Multiple gestation, Previous Abortions, Previous intrauterine surgery, placenta previa in previous pregnancy, Smoking.

Objective:

Identification of risk factors, the feto-maternal outcome and complications of patients having placenta previa with previous caesarean section.

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“Make My Burden Lighter”: Depression and Social Support in Persons with Disability in Ghana

Abstract:

Depression in the general population has been associated with inadequate or lack of social support. Evidence from the disability field has been limited. This study investigated the relationship of perceived social support to depression in Persons with Disability (PWDs) using a descriptive survey design. Data was collected from 317 PWDs using the Beck Depression Inventory Scale (BDI) and Multidimensional Scale of Perceived Social Support (MSPSS) and analyzed with Statistical Package for the Social Sciences (SPSS) version 16 software. Findings revealed significant relationship between perceived social support and depression in PWDs and meaningful social support ameliorated severity of depressive symptoms. Though etiology of acquisition of the disability, either by birth or later in life, had less likelihood on being depressed, respondents who acquired their disability later in life had significant depression levels than those who were born disabled. Implications...

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Delayed Diagnosis of Glioblastoma due to Recent Ruptured Aneurysm. A Case Report.

Abstract:

Rupture of an intracranial aneurysm may cover for a long time clinical and radiological signs of a coexistent tumor. We report the delayed diagnosis of glioblastoma in a 65-years old female with recent history of subarachnoid hemorrhage. In the literature are described few similar cases: we briefly discuss the management in the rare occurrence of a double neurosurgical disease.

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Live Pregnancy in Non Communicating Horn of Unicornuate Uterus with Placenta Percreta: A Case Report and Review

Abstract:

Objective:

Mullerian anomalies of the female genital tract are rare and unicornuate uterus is one such variant: it may present with a rudimentary horn with or without a communication. Pregnancy is rare in a non communicating horn and majority of them end up in rupture during first trimester. The ones which progress to fetal viability are around 10 % and may end up in catastrophic hemorrhage with fetal loss at any time.

Case report:

We hereby report a rare case of unruptured rudimentary horn pregnancy associated with placenta accreta and delivery of a live born fetus at 34 weeks period of gestation. Around ten cases of such an association have been reported in the past.

Conclusion:

Diagnosis of pregnancy in a non communicat...

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Evidence for the Absence of La Crosse Virus, Rift Valley Fever Virus, and Bunyamwera Virus in Korean Domestic Pigs

Abstract:

A surveillance study reports no detection of targeted bunyaviruses in domestic pigs in Korea. Methods, sampling frame, and assay limits are described to contextualize interpretation and surveillance value.

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Protective Effect of Fennel Oil on Cyclophosphamide Inhibited Spermatogenesis and Induced Oxidative Stress in Albino Rats.

Abstract:

Introduction:

Cyclophosphamide (CPA) is an anticancer drug .Fennel (Foeniculum vulgare Mill) essential oil is a traditional medicine used against many diseases.

Aim.

The present work studied the effect of fennel oil against testicular damage and oxidative stress induced by the anticancer drug, cyclophosphamide (CPA) in albino rats.

Methods.

Animals were divided into 4 groups: group1, control, group2, orally given fennel oil, group3 treated with CPA and group4 treated with CPA and fennel oil. The testes were removed for histological and immune histochemical preparation. Blood was collected and sera were prepared for hormonal and biochemical analysis.

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Volvulus of the Small Bowel Due to Malrotation During Pregnancy: A Case-Report

Abstract:

Volvulus occurring during pregnancy is a rare complication, still potentially lethal nowadays for both the mother and child due to several, early arising complications. We report here a case of small bowel volvulus in a 28 weeks and 4 days, 29 years-old, pregnant woman with a past medical history of appendectomy in her childhood. Patient presented in emergency department with abdominal pain and abnormal hepatic tests. Cholangio-MRI suggested bowel obstruction due to volvulus that was confirmed by gastroscopy (showing the obstruction) and intestinal MRI. Patient was first treated by laparoscopy but, due to a very complicated abdominal status with the presence of several adhesions of the small bowel, surgery was changed to an open laparotomy, which allowed discovery and repositioning of small bowel malrotation and removal of adhesions. Both patient and the foetus were healthy after surgery and the patient was then discharged. In the light of this particularly rare c...

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Association of Gestational Diabetes and Proinflammatory Cytokines (IL-6, TNF-α and IL-1β)

Abstract:

Changes to proinflammatory cytokines as a result of gestational diabetes mellitus (GDM), and the pregnancy complications that these changes can cause, are of vital importance to the effective prevention and optimal management. Interleukin-6 (IL-6), interleukin-1 beta (IL-1β), and tumor necrosis factor alpha (TNF-α) are cytokines that are associated with gestational diabetes. Therefore, the aim of this review is to draw attention to the relationship between gestational diabetes and these diseases

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Religion and Mental Health: A Critical Reflection in Consequence of Four Reviews (1969-2013)

Abstract:

Religion and spirituality correlate positively with mental health. Although it is true generally spoken, it is too simplistic. On the basis of four reviews, from the period 1969-2013, the progress that was made and the achievements that were accomplished will be shown. In doing their empirical work the researchers managed to fit in with the evidence-based medicine approach. Thus, their work corresponded more and more to the standard scientific requirements. However, what are the consequences of that fit? And, in what sense could religion become part of ‘the most effective means of achieving health’? That asks for a critical ethical evaluation. Utilitarianism turns out to be the ethical basis of evidence-based medicine and achieving health is its central value. As a consequence, compared with religious traditions religion gets a different content with a strong experiential-expressive focus. That focus fits perfectly with modern Western values. Finally, the find...

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