Dilsiz Alparslan, Ozone Therapy in the Treatment of Periodontal Disease, Journal of Dentistry And Oral Implants, Volume 2, Issue 1, 2018, Pages 15-17, ISSN 2473-1005, https://doi.org/10.14302/issn.2473-1005.jdoi-18-2076. (https://oap-researcharticles.org/jdoi/article/769) Abstract: This review examines the adjunctive use of ozone therapy for periodontal disease. It summarizes proposed antimicrobial and host‑modulating effects, delivery methods, and safety considerations, and calls for standardized trials to define clinical benefit. Keywords: Periodontal diseases; periodontal therapy; Ozone; Ozone tolerance; antimicrobial; immunostimulating; antihypoxic; antioxidants