P. Storey Philip, A. Philander Shannon, J. Wong Brandon, Rao Narsing, C. Rodger Damien, Recurrent branch retinal arterial occlusions associated with plasminogen activator inhibitor-1 mutation, Journal of Ophthalmic Science, Volume 1, Issue 4, 2017, Pages 15-19, ISSN 2470-0436, https://doi.org/10.14302/issn.2470-0436.jos-17-1721.
(https://oap-researcharticles.org/jos/article/566)
Abstract: A 57-year-old Hispanic female presented with 3 days of blurry vision in the left eye. Eight years prior, she had a branch retinal artery occlusion in the right eye and a hematologic work-up revealed a 4G/4G polymorphism in plasminogen activator inhibitor-1. With the current episode, she was found to have bilateral branch retinal artery occlusions and mild vitritis in the left eye, simulating a toxoplasma infection. An infectious and inflammatory work up, however, was negative and the vitritis resolved after a short course of steroids. Plasminogen activator inhibitor-1 mutations may be associated with an increased risk of retinal vascular occlusions.
Keywords: retinal artery occlusion; plasminogen activator inhibitor