Akonu Adom Mensah Forson Kwesi, Tridax Procumbens Inhibitory Properties of Alpha Amylase, International Journal of Biochemistry Advances, Volume 1, Issue 1, 2021, Pages 9-30, ISSN 0000-0000, https://doi.org/.
(https://oap-researcharticles.org/ijba/article/1883)
Abstract: The purpose of this study was to investigate the effects of extracts of Tridax procumbens leaves a traditional medicinal plant, on α-amylase activities in vitro. The air-dried aerial parts of Tridax procumbens leaves were extracted with Petroleum ether and Ethanol. The results of both enzyme inhibition activities were found in a dose-dependent manner. The strongest activity of α-amylase inhibition was found in Petroleum ether extract (IC50 = 10.436 mg/mL) followed by ethanol extract  (IC50 = 12.65 mg/mL) compared with acarbose having an IC50 value of 0.044 mg/mL. All extracts from this plant possess potent α-amylase activity inhibition which may offer a better therapeutic strategy to minimize postprandial hyperglycemia and its complications.  
Keywords: Tridax procumbens; alpha-amylase activity; Diabetes Mellitus